Dr. Guillermo Delgado Lamas

El Dr. Guillermo Delgado imparte las asignaturas de Química Orgánica a nivel Licenciatura y Posgrado, entre otras, y ha coordinado diversos seminarios a nivel Doctorado. Ha dirigido más de 110 tesis, de las cuales más de la mitad de ellas corresponden a los niveles de maestría y doctorado. Es tutor acreditado en Programas de Posgrado en Ciencias Químicas y en Ciencias Biomédicas de la UNAM. Tiene disponibilidad para aceptar alumnos de Licenciatura, Maestría y Doctorado, posdoctorantes y huéspedes académicos.

• Distinción Universidad Nacional para Jóvenes Académicos en el área de Investigación en Ciencias Naturales. 1989.
• Premio de Investigación en Ciencias Exactas de la actual Academia Mexicana de Ciencias. 1992.
• Premio Nacional de Química Andrés M. del Río, en el área de investigación, otorgado por la Sociedad Química de México en 2003.
• Editor de la Revista de la Sociedad Química de México, actual Journal of the Mexican Chemical Society (1996-2006).
• Coordinador del Programa de Maestría y Doctorado en Ciencias Químicas de la UNAM (2005-2007).
• Presidente (2007-2009) y Vicepresidente (2005-2007) de la Sociedad Química de México.
• Miembro del Sistema Nacional de Investigadores desde 1984, donde actualmente es Nivel III.

• El Dr. Guillermo Delgado ha impartido alrededor de 70 conferencias en eventos científicos nacionales e internacionales, y ha participado en más de 180 presentaciones en diversos eventos de divulgación. Es autor de dos libros, de 15 capítulos en libros y de varios artículos de difusión. 

• Lecturas temáticas de divulgación.
  

Ávila, J. L.; Almeida-Aguirre, E. K. P.; Méndez-Cuesta, C. A.; Toscano, R. A.; Cerbón Cervantes, M. A.; Delgado, G. Structural Reassignment of rel-(3’Z,3R,6R,7R,3a’R, 6’R)-3,8-dihydrodiligustilide and the Activity of Diligustilide, 3,8-Dihydro, and 3,5,7’,7’a-Tetrahydrodiligustilides as Progestins. Organic Letters 2019, 21, 7460-7465 doi: 10.1021/acs.orglett.9b02762

Rodríguez-Chávez, J. L.; Méndez-Cuesta, C. A.; Ramírez-Apan, T.; Egas, V.; Ávila, J. L.; Neira-González, A.; Hernández, T.; Espinosa-García, F. J., Delgado, G. Chemo-sensitizing activity of natural cadinenes from Heterotheca inuloides in human uterine sarcoma cells and their in silico interaction with ABC transporters. Bioorg. Chem. 91, 2019. doi.org/10.1016/j.bioorg.2019.103091

Rodríguez-Chávez, J. L.; Juárez-Campuzano, Y. S.; Delgado, G.; Pacheco Aguilar, J. R. Identification of lipoproteins from Bacillus strain Q11 with ability to inhibit the germination of Penicillum expansum, the etiological agent of postharvest blue mold disease. Post Harvest Biology and Technology. https://doi.org/10.1016/j.postharvbio.2019.05.011

Rodríguez-Chávez, J. L.; Franco-Navarro, F.; Delgado, G. In vitro nematicidal activity of natural and semisynthetic cadinenes from Heterotheca inuloides against plant-parasitic nematode, Nacobbus aberrans (Tylenchida: Pratylenchidae). Pest Management Science 2019. https://doi.org/10.1002/ps.5294

Egas, V.; Salazar-Cervantes, G.; Romero, I.; Méndez-Cuesta, C. A.; Rodríguez-Chávez, J. L.; Delgado, G. Anti-Helicobacter pylori metabolites from Heterotheca inuloides. Fitoterapia 2018, 127, 314-321 ISSN 0367326X  doi: 10.1016/j.fitote.2018.03.001

Cano-Flores, A.; Delgado, G. Transformations of Some Sesquiterpene Lactones by Filamentous Fungi. Cytotoxic Evaluation of the Natural Compounds and the Biotransformed Products. Chemistry and Biodiversity 2017 e1700211 Doi: 10.1002/cbdv.201700211/epdf

Egas, V.; Millán, E.; Collado, J. A.; Ramírez-Apan, T.; Méndez-Cuesta, C. A.; Muñoz, E.; Delgado, G. Natural and semisynthetic cadinanes from Heterotheca inuloides target NF-kB and Nrf2 transcription factors and display in vitro cytotoxicity over human cancer cell lines. Bioorganic and Medicinal Chemistry 2017, 25, 3135-3147. http://dx.doi.org/10.1016/j.bmc.2017.03.069

Novillo, F.; Rosero, V.; Chávez, M. I.; Hernández-Ortega, S.; Martínez, E. M.; Delgado, G.

Tonantzitlolone A and other cytotoxic constituents of Sapium macrocarpum (Euphorbiaceae). J. Mex. Chem. Soc. 2017, 61 (1), 67-73. EID: 2-s2.0-85020092091

Rodríguez-Chávez, J. L.; Egas, V.; Linares, E.; Bye, R.; Hernández, T.; Espinosa-García, F. J.; Delgado, G. Mexican Arnica (Heterotheca inuloides Cass. Asteraceae: Astereae): Ethnomedical uses, chemical constituents and biological properties. Journal of Ethnopharmacology 2017, 195, 39-63. Doi: 10.1016/j.jep.2016.11.021 

Bravo-Monzón, A. E.; Ríos Vásquez, E.; Delgado-Lamas, G.; Espinosa-García, F. J. Differential herbivory of the specialist beetle Stolas punicea on chemical phenotypes of its host Mikania micrantha. Biocontrol Science and Technology 2016, 26 (3):1-15. DOI: 10.1080/09583157.2015.1118436.

Rodríguez-Chávez, J. L.; Gómez-Vidales, V.; Coballase-Urrutia, E.; Ortega-Cuéllar, D.; Delgado-Lamas, G. Heterotheca inuloides (Mexican arnica) metabolites protect Caenorhabditis elegans from oxidative damage and inhibit nitric oxide production. RSC Advances 2016, 6, 12032-12041. DOI: 10.1039/c5ra21646j

Egas, V.; Toscano, R A.; Linares, E.; Bye, R.; Espinosa-García, F. J.; Delgado, G. Cadinane-Type Sesquiterpenoids from Heterotheca inuloides. Absolute Configuration and Anti-inflammatory Activity. J. Nat. Prod. 2015, 78, 2634-2641. Doi: 10.1021/acs.jnatprod.5b00571

Rodríguez-Chávez, J. L.; Coballase-Urrutia, E.; Sicilia-Argumedo, G.; Ramírez-Apan, T.; Delgado, G. Toxicological evaluation of the natural products and some semisynthetic derivatives of Heterotheca inuloides Cass (Asteraceae). Journal of Ethnopharmacology 2015, 175, 256-265. Doi: 10.16/j.jep.2015.08.055

Martínez-Díaz, Y.; González-Rodríguez, A.; Delgado-Lamas, G.; Espinosa-García, F. J. Geographic structure of chemical variation in wild populations of the fuel crop Jatropha curcas L. in Mexico. Industrial Crops and Products 2015, 74, 63-68  

Doi: 10.1016/j.indcrop.2015.04.049

Rodríguez-Chávez, J. L.; Coballase-Urrutia, E.; Nieto-Camacho, A.; Delgado-Lamas, G.  Antioxidant Capacity of Mexican Arnica. Heterotheca inuloides Cass Natural Products and SomeDerivatives: Their Anti-Inflammatory Evaluation and Effect on C. elegans Life Span. Oxidative Medicine and Cellular Longevity. Volume 2015 (2015), Article ID 843237.  Doi: 10.1155/2015/843237   PMID: 25821555

Rodríguez-Chávez, J. J.; Rufino-González, Y.; Ponce-Macotela, Y.; Delgado, G. In vitro activity of Mexican arnica Heterotheca inuloides Cass natural products and some derivatives against Giardia intestinalis. Parasitology 2015, 142, 576-584. Doi: 10.1017/S0031182014001619     PMID: 25363565

Del Angel, M.; Nieto, A.; Ramírez-Apan, T.; Delgado, G. Antiinflammatory Effect of Natural and Semisynthetic Phthalides. Eur. J. Pharmacol. 2015, 752, 40-48. Doi: 10.1016/j.ejphar.2015.01.0  

Bravo-Monzón, A. E.; Ríos-Vásquez, Delgado, G.; Espinosa-García, F. J. “Chemical diversity among populations of Mikania micrantha: geographic mosaic structure and herbivory”. Oecologia 2014, 174, 195-203. Doi: 10.1007/s00442-013-2748-y 

Ríos, E.; León, A.; Chávez, M. I.; Torres, Y.; Ramírez Apan, M. T.; Toscano, R. A.; Bravo-Monzón, A. E.; Espinosa-García, F. J.; Delgado, G. “Sesquiterpene Lactones from Mikania micrantha and Mikania cordifolia and their cytotoxic and anti-inflammatory evaluation”. Fitoterapia 2014, 94, 155-163. Doi: 10.1016/j.fitote.2014.02.006 

Cadena, R. N.; Ríos, E.; Jorge, I. S.; John, C. C.; Delgado, G. “Secondary metabolites from Mikania micrantha collected in the department of Quindio (Colombia) and preliminary evaluation of the antimicrobial activity”. Rev. Invest. Univ. Quindio 2013 (2), 293-301. Publisher: Universidad del Quindio. CODEN: RIUQAJ ISSN: 1794-631X 

León, A.; Delgado, G. Diligustilide: Enantiomeric Derivatives, Absolute Configuration and Cytotoxic Properties”. Journal of the Mexican Chemical Society 2012, 56, 222-226. EID: 2-s2.0-84864878991

León, A.; Cogordán, J. A.; Sterner, O.; Delgado, G. Enantiomeric Derivatives of Tokinolide B: Absolute Configuration and Biological Properties. Journal of Natural Products 2012, 75, 859-864. DOI: 10.1021/np200645p  PMID: 22574648 

León, A.; Chávez, M. I.; Delgado, G. 1H and DOSY NMR Spectroscopy analysis of Ligusticum porteri rhizome extracts. Magnetic Resonance in Chemistry 2011, 49, 469-476. Doi: 10.1002/mrc.2767  PMID: 21761449

León, A.; Toscano, R. A.; Tortoriello, J.; Delgado, G. Phthalides and Other Constituents from Ligusticum porteri. Sedative and Spasmolytic Activities of Some Natural Products and Derivatives. Natural Product Research 2011, 25, 1234-1242.  PMID: 21797735. Doi: 10.1080/14786419.2010.534735   

Torres-Gurrola, G.; Delgado Lamas, G.; Espinosa-García, F. J. The foliar chemical profile of criollo avocado, Persea americana var. drymifolia (Lauraceae), and its relationship with the incidence of a gall forming insect, Trioza anceps (Triozidae). Biochememical Systematics and Ecology 2011, 39, 102-111. doi:10.1016/j.bse.2011.01.011

Cano, A., Ramírez Apan, M. T.; Delgado, G. Transformation of Sclareolide by Filamentous Fungi: Cytotoxic Evaluations of the Derivatives. Journal of the Brazilian Chemical Society 2011, 22, 1177-1182.

doi: 10.1590/S0103-50532011000600025 

León, A.; Toscano, R. A.; Cogordán, J. A.; Delgado, G. “Differentiated Cyclization of the Keto Acid Derived from Tokinolide B”. Heterocycles 2011, 82, 1567-1576. DOI: 10.3987/COM-10-S(E)113

Narváez-Mastache, J. M.; Soto, C.; Delgado, G. Hypoglycemic and Antioxidant Effects of Subcoriacin in Normal and Streptozotocin-induced Diabetic Rats. J. Mex. Chem. Soc. 2010, 54, 240-244. EID: 2-s2.0-79551547083

Reyes, B. M.; Ramírez-Apan, M. T.; Toscano, R. A.; Delgado, G. Triterpenes from Garcia parviflora. Cytotoxic Evaluation of Natural and Semisynthetic Friedelanes. Journal of Natural Products 2010, 73, 1839–1845. DOI: 10.1021/np060194h

Arellano-Martínez, R.; Delgado, G. Hypargyrin A, a Hemiacetalic Germacrolide from Viguiera hypargyrea (Asteraceae). Biogenetic Implications and Biological Evaluation. Journal of the Mexican Chemical Society 2010, 54, 117-121. EID: 2-s2.0-77956430964

Coballase-Urrutia, E.; Pedraza-Chaverri, J.; Camacho-Carranza, R.; Cárdenas-Rodríguez, N.; Huerta-Gertrudis, B.; Medina-Campos, O. N.; Mendoza-Cruz, M.; Delgado-Lamas, G.; Espinosa-Aguirre, J. J.  Antioxidant activity of Heterotheca inuloides extracts and of some of its metabolites. Toxicology 2010, 276, 41-48. DOI: 10.1016/j.tox.2010.06.013

León, A.; Reyes, B. M.; Chávez, M. I.; Toscano, R. A.; Delgado, G. Sesquiterpene Lactones, Acyl Phenyl Propanoids and Other Constituents from Schkuhria pinnata var. wislizeni. Antioxidant Evaluation. Journal of the Mexican Chemical Society 2009, 53, 192-200. ISSN 1870-249X, EID: 2-s2.0-77953185257

Camacho-Corona, M. R.; Favela-Hernández, M. J.; González-Santiago, O.; Garza-González, E.; Molina-Salinas, G. M.; Said-Fernández, S.; Delgado, G.; Luna-Herrera, J. Evaluation of Some Plant-derived Secondary Metabolites Against Sensitive and Multidrug-resistant Mycobacterium tuberculosis. Journal of the Mexican Chemical Society. 2009, 53, 71-75. EID: 2-s2.0-77952917752

Maldonado-López, Y.; Linares-Mazari, E.; Bye, R.; Delgado, G.; Espinosa-Garcia, F. J.  Mexican arnica anti-inflammatory action: plant age is correlated with the concentration of anti-inflammatory sesquiterpenes in the medicinal plant Heterotheca inuloides Cass. (Asteraceae). Economic Botany 2008, 62, 161-170. DOI: 10.1007/s12231-008-9015-x

Ergaz, I.; Toscano, R. A.; Delgado, G.; Steinberg, A.; Glaser, R. The Effect of Environment on Molecular Structure: the Crystalline-State Stereochemistry of N-methylated Adamantane 1,3-Diammonium Salts. Crystal Growth and Design 2008, 8, 1399-1405.  DOI: 10.1021/cg0704908

Narváez-Mastache, J. M.; Novillo, F.; Delgado, G. Antioxidant arylprenylcoumarin, flavan-3-ols and flavonoids from Eysenhardtia subcoriacea. Phytochemistry 2008, 69, 451-456. doi:10.1016/j.phytochem.2007.07.019

Wilmer Perera, Clara Nogueiras, Armando Payo, Guillermo Delgado, Beatriz Quiroz, Rosa Sarduy and Marledis Oquendo. Flavonols from leaves of Pluchea carolinensis (Jacq.) G. Don (Asteraceae). Rev. Latinoam. Quím. 2007, 35, 68-73. 

Narváez-Mastache, J. M.; Soto, C.; Delgado, G. Antioxidant evaluation of Eysenhardtia species (Fabaceae): relay synthesis of 3-O-Acetyl-11α ,12α -epoxy-oleanan-28,13β -olide isolated from E. platycarpa and its protective effect in experimental diabetes. Biological & Pharmaceutical Bulletin 2007, 30, 1503-1510. DOI: 10.1248/bpb.30.1503

Lager, E.; Sundin, A.; Toscano, R. A.; Delgado, G.; Sterner, O. Diels-Alder adducts derived from the natural phthalide Z-ligustilide. Tetrahedron Letters 2007, 48, 4215-4218. doi:10.1016/j.tetlet.2007.04.059

García, A.; Delgado, G. Constituents from Tithonia diversifolia. Stereochemical Revision of 2α-Hydroxytirotundin. Journal of the Mexican Chemical Society 2006, 50, 180-190. 

Perera Córdoba, W. H.; González Mesa, L.; Payo Hill, A. L.; Nogueiras Lima, C.; Delgado Lamas, G.; Oquendo Suárez, M.; Sarduy Domínguez, R. Antimicrobial Activity of Crude Extracts and Flavonoids from Leaves of Pluchea carolinensis (Jacq.) G. Don. Pharmacologyonline 2006, 3, 757-761.

Narváez-Mastache, J. M.; Garduño-Ramírez, M. L.; Álvarez, L.; Delgado, G. Antihyperglycemic Activity and Chemical Constituents of Eysenhardtia platycarpa. Journal of Natural Products 2006, 69,1687-1691. DOI: 10.1021/np060166z

García, A.; Ramírez-Apan, T.; Cogordan, J. A.; Delgado, G. Absolute configuration assignments by experimental and theoretical approaches of ent-labdane and cis-ent-clerodane-type diterpenes isolated from Croton glabellus. Canadian Journal of Chemistry 2006, 84, 1593-1602. doi.org/10.1139/v06-164

García, A.; Delgado, G. Cytotoxic cis-Fused Bicyclic Sesquiterpenoids from Jatropha neopauciflora. J. Nat. Prod. 2006, 69, 1618-1621. DOI: 10.1021/np060194h

Encarnación-Dimayuga, R.; Agúndez-Espinoza, J.; García, A.; Delgado, G.; Molina-Salinas, G. M.; Said-Fernández, S. Two New Cassane-Type Diterpenes from Calliandra californica with Antituberculosis and Cytotoxic Activities. Planta Medica 2006, 72, 757-760. DOI: 10.1055/s-2006-931587

Cano, A.; Espinoza, M.; Ramos, C. H.; Delgado, G. New Prenylated Flavanones from Esenbeckia berlandieri ssp acapulcencis. Journal of the Mexican Chemical Society. 2006, 50, 71-75. 

García, A.; Delgado, G. Uncommon Sesquiterpenoids and New Triterpenoids from Jatropha neopauciflora (Euphorbiaceae). Helv. Chim. Acta 2006, 89, 16-29. https://doi.org/10.1002/hlca.200690009

Glaser, R.; García, A.; Chávez, M. I.; Delgado, G. The Solid-State and Solution-State Structures of Tagitinin A, a 3,10-Epoxy-Germacrolide from Tithonia diversifolia, and the Interconversion of 3,10-Epoxy-Germacrolide Conformational Families via a Ring-Atom Flip Mechanism. J. Mex. Chem. Soc. 2005, 49, 202-210; J. Braz. Chem. Soc. 2005, 16, 440-448 (Joint Issue). http://dx.doi.org/10.1590/S0103-50532005000300019

Quiroz-García, B.; Figueroa, R.; Cogordan, J. A.; Delgado, G. Photocyclodimers from Z-Ligustilide. Experimental Results and FMO Analysis. Tetrahedron Letters 2005, 46, 3003-3006. DOI: 10.1016/j.tetlet.2005.03.024. EID: 2-s2.0-15944362235

Quiroz-García, B.; Hernández-Ortega, S.; Sterner, O.; Delgado, G. Transformations of the Natural Dimeric Phthalide Diligustilide. Tetrahedron 2004, 60, 3681-3688. DOI: 10.1016/j.tet.2004.02.045, EID: 2-s2.0-1842420335

Delgado, G.; Krishnamurthy, R. Assignment of the 1H and 13C NMR Spectra of N2,N6-Dibenzoyl-N2,N9-bis(2’,3’-di-O-benzoyl-(α)-L-threofuranosyl)-2,6-diamino-purine. Rev. Soc. Quím. Méx. 2003, 47, 216-220. 

González-Bernardo, E.; Aguilar, M. I.; Delgado, G.; King-Díaz, B.; Lotina-Hennsen, B. Photosynthetic Electron Transport Interaction of Xanthorrhizol Isolated from Iostephane heterophylla and its Derivatives. Physiologia Plantarum 2003, 119, 598-604. https://doi.org/10.1046/j.1399-3054.2003.00180.x

Garduño-Ramírez, M. L.; Delgado, G. New Eremophilanoids from the Roots of Psacalium radulifolium. Hypoglycemic, Antihyperglycemic and Anti-Oxidant Evaluations. Revista de la Sociedad Química de México (J. Mex. Chem. Soc.) 2003, 47, 160-166. 

Quiroz, B.; Hernández, L.; Toscano, R. A.; Sterner, O.; Delgado, G. Base Catalyzed Intramolecular Condensation of Tokinolide B. Tetrahedron Lett. 2003, 2509-2512. DOI: 10.1016/S0040-4039(03)00291-0, EID: 2-s2.0-0037450919

Chávez, M. I.; Julián, A.; Delgado, G. Structure Elucidaton and 13C NMR Spectral Assignments of 3α-Hydroxyolean-12-en-30-oic acid, a New Triterpene from Bocconia arborea. Magnetic Resonance in Chemistry 2003, 41, 143-144. DOI: 10.1002/mrc.1144, EID: 2-s2.0-0142134892

Zamilpa, A.; Tortoriello, J.; Navarro, V.; Delgado, G. Alvarez, L. Five New Steroidal Saponins from Solanum chrysotrychum and their Antimycotic Activity. Journal of Natural Products 2002, 65, 1815-1819. DOI: 10.1021/np020261h, EID: 2-s2.0-0036932560

Vázquez, E.; Martínez, E. M.; Cogordán, J. A.; Delgado, G. Triterpenes, Phenols, and Other Constituents from Ochroma pyramidale (Balsa Wood, Bombacaceae). Preferred Conformations of 8-C-β-D-Glucopyranosyl-apigenin (Vitexin). Rev. Soc. Quím. Méx. 2002, 46, 254-258. 

Rios, M. Y.; Aguilar-Guadarrama, A. B.; Delgado, G. Furoquinoline Alkaloids, Furocoumarins and Terpenes from Esenbeckia litoralis (Rutaceae). Biochem. Syst. Ecol. 2002, 30, 977-979. DOI: 10.1016/S0305-1978(02)00042-X

Schöning, K.-U.; Scholz, P.; Wu, X.; Guntha, S.; Delgado, G.; Krishnamurthy, R.; Delgado, G.; Eschenmoser, A. The α-L-Threofuranosyl-(3’-2’)-Oligonucleotide System (“TNA”): Synthesis and Pairing Properties. Helvetica Chimica Acta 2002, 85, 4111-4153. https://doi.org/10.1002/hlca.200290000

Rios, M. Y.; Delgado, G. Furocoumarins, Terpenes and Sterols from Esenbeckia ovata Kunth (Rutaceae). Biochem. Syst. Ecol. 2002, 30, 697-699. DOI: 10.1016/S0305-1978(01)00138-7

Gómez, C.; Saldívar González, A.; Delgado, G.; Rodríguez-Carranza, R. Rapid Anxiolytic Activity of Progesterone and Pregnanolone in Male Rats. Pharmacology, Biochemistry and Behavior 2002, 72, 543-550. https://doi.org/10.1016/S0091-3057(02)00722-0

Zamilpa, A.; Tortoriello, J.; Navarro, V.; Delgado, G.; Álvarez, L. Antispasmodic and Antimicrobial Diterpenic Acids from Viguiera hypargyrea Roots. Planta Medica 2002, 68, 281-283. DOI: 10.1055/s-2002-23146

Wu, X.; Delgado, G.; Krishnamurthy, R.; Eschenmoser, A. 2,6-Diaminopurine in TNA. Effect on Duplex Stabilities and on the Efficiency of the Template Controlled Ligations. Organic Letters 2002, 4, 1283-1286. (FI: 6.579). DOI: 10.1021/ol020016p

Gamboa-Angulo, M. M.; Escalante-Erosa, F.; García Sosa, K.; Alejos González, F.; Delgado, G.; Peña Rodríguez, L. Natural Zinniol Derivatives from Alternaria tagetica. Isolation, Synthesis and Structure Activity Correlation. J. Agric. Food Chem. 2002, 49, 1053-1058. DOI: 10.1021/jf010641t

Gamboa-Angulo, M. M.; García-Sosa, K.; Alejos-González. F.; Escalante-Erosa, F.; Delgado, G.; Peña-Rodríguez, L. M. Tagetolone and Tagetenolone: Two Phytotoxic Polyketides from Alternaria tagetica. J. Agric. Food Chem. 2001, 49, 1228-1232. DOI: 10.1021/jf000872k

Julián, A.; Delgado, G. Bocconarborines A and B, Novel 1,3-Bis-Benzophenanthridine Acetone Alkaloids from Bocconia arborea. Rev. Soc. Quím. Méx. 2001, 45, 189-194. 

Aguilar, M. I.; Delgado, G.; Villarreal, M. L. New Bioactive Derivatives of Xanthorrhizol. Rev. Soc. Quím. Méx. 2001, 45, 56-59. 

Aguilar, M. I.; Delgado, G.; Hernández, M. L.; Villarreal, M. L. Bioactive Compounds from Iostephane heterophylla (Asteraceae). Nat. Prod. Lett. 2001, 15, 93-101. DOI: 10.1080/10575630108041265 

Delgado, G.; Olivares, M. S.; Chávez, M. I.; Ramírez-Apan, T.; Linares, E.; Bye, R; Espinosa-García, F. J. Anti-inflammmatory Constituents from Heterotheca inuloides. J. Nat. Prod. 2001, 64, 861-864. DOI: 10.1021/np0005107

Garduño-Ramirez, M. L.; Trejo, A.; Navarro, V.; Linares, E.; Bye, R.; Delgado, G. New Modified Eremophilanes from the Roots of Psacalium radulifolium. J. Nat. Prod. 2001, 64, 432-435. DOI: 10.1021/np000385z

Marquina, S.; Maldonado, N.; Garduño-Ramírez, M. L.; Aranda, E.; Villarreal, M. L.; Navarro, V.; Bye, R.; Delgado, G.; Álvarez, L. Bioactive Oleanolic Acid Saponins and Other Constituents from the Roots of Viguiera decurrens. Phytochemistry 2001, 56, 93-97. DOI: 10.1016/S0031-9422(00)00283-1

Guerrero, B.; Castillo, J.; Aguilar, M.I.; Delgado, G.; 5α,7β,10β,13α-Pentaacetoxy-4(20),11-Taxadiene (7β-Acetoxy-Taxusin) and Other Constituents from the Bark of the Mexican Yew, Taxus globosa (Taxaceae). Rev. Soc. Quím. Méx. 2000, 44, 148-150. 

Gamboa Angulo, M. M.; Alejos, F.; Escalante, F.; Delgado, G.; and Peña Rodríguez, L. Novel Dimeric Metabolites from Alternaria tagetica. J. Nat. Prod. 2000, 63, 1117-1120. DOI: 10.1021/np990422q

Campos, M.G.; Oropeza, M.V., Villanueva, T.; Aguilar, M.I.; Delgado, G. Xanthorrhizol Induced Endothelium-Independent Relaxation of Rat Thoracic Aorta. Life Sciences 2000, 67, 327-333. DOI: 10.1016/S0024-3205(00)00619-6

Rios, M. Y.; Delgado, G. Lewis Acid Catalyzed Transformations of Z-Ligustilide. Rev. Soc. Quím. Méx. 43, 127-132 (1999). 

Delgado, G.; Guzmán, S. Stereoselective Entry to the Bicycle [4.3.0] Skeleton of Oplopanes Using a Transannular Cyclization Strategy. Synlett 1999, 1006-1008. DOI: 10.1055/s-1999-3121

Ponce-Monter, H.; Campos, M. G.; Aguilar, M. I.; Delgado, G. Effect of Xanthorrhizol, Xanthorrizol Glycoside and Trachylobanoic Acid Isolated from Cachani Complex Plants Upon the Contractile Activity of Uterine Smooth Muscle. Phytotherapy Research 1999, 13, 202-205. https://doi.org/10.1002/(SICI)1099-1573(199905)13:3<202::AID-PTR418>3.0.CO;2-R

Navarro, V.; Delgado, G. Two Antimicrobial Alkaloids from Bocconia arborea. Journal of Ethnopharmacology 1999, 66, 223-226. DOI: 10.1016/S0378-8741(98)00182-2

Alvarez, L.; Delgado, G. C- and O- Glycosyl-α-Hydroxy Chalcones from Eysenhardtia polystachya. Phytochemistry 1999, 50, 681-687. https://doi.org/10.1016/S0031-9422(98)00576-7

Rios, M. Y.; Delgado, G.; Espinosa-Pérez, G. Base-Catalyzed Intramolecular Condensations of Diligustilide. Tetrahedron Letters 1998, 39, 6605-6608. https://doi.org/10.1016/S0040-4039(98)01394-X

Delgado, G.; Tejeda, V.; Salas, A.; Chávez, M. I.; Guzmán, S.; Bolaños, A.; Aguilar, M. I.; Navarro, V.; Villarreal, M. L. New Bioactive Melampolides from Schkuhria schkuhrioides. Journal of Natural Products 1998, 61, 1082-1085. DOI: 10.1021/np970548s

Álvarez, L.; Ríos, M. Y.; Esquivel, C.; Chávez, M. I.; Delgado, G.; Aguilar, M. I.; Villarreal, M. L.; Navarro, V. Cytotoxic Isoflavans from Eysenhardtia polystachya. Journal of Natural Products 1998, 61, 767-770. DOI: 10.1021/np970586b

Navarro, V.; Rojas, G.; Delgado, G.; Lozoya, X. Antimicrobial Compounds Detected in Bocconia arborea Extracts by a Direct Bioautographic Method. Archives of Medical Research 1998, 29, 191-194. EID: 2-s2.0-0031832173. PMID:9650337

Espinosa-García, F.; Delgado, G. Relationship Between Ecology of Plant Defense and the Prospection of Secondary Metabolites with Potential Medicinal or Agricultural Application. Revista Latinoamericana de Química 1988, 26, 13-29. 

Delgado, G.; Tejeda, V. Acylated Phenyl Propanoids from Schkuhria schkuhrioides. Natural Products Letters 12, 17-22 (1998). DOI: 10.1080/10575639808048865

Rios, M. Y.; Delgado, G.; Toscano, R. A. Chemical Reactivity of Phthalides. Relay Synthesis of Diligustilide, Rel-(3’R)-3’,8’-Dihydrodiligustilide and Wallichilide. Tetrahedron 1998, 54, 3355-3366. https://doi.org/10.1016/S0040-4020(98)00080-5

Malagón, F.; Vázquez, J.; Delgado, G.; Ruiz, A. Antimalaric Effect of an Alcoholic Extract of Artemisia ludoviciana ssp mexicana in a Rodent Malaria Model. Parassitologia 1997, 39, 3-7. PMID: 9419840

Delgado, G.; García, P.; Roldan, R. I.; Bye, R.; Linares, E. New Eremophilane Sesquiterpene Lactones from the Roots of Roldana sessilifolia. Natural Product Letters 1996, 8, 145-150. https://doi.org/10.1080/10575639608043254

Álvarez, L.; Marquina, S.; Villarreal, M. L.; Alonso, D.; Aranda, E.; Delgado, G.; Bioactive Polyacetylenes from Bidens pilosa. Planta Medica 1996, 62, 355-356. DOI:

10.1055/s-2006-957902

Aguilar, M. I.; Delgado, G. Novel Bisabolene Glycoside and Other Constituents from the Roots of the Medicinal Plant Iostephane heterophylla (Asteraceae). Natural Product Letters 1995, 7, 155-162. Doi: 10.1080/10575639508043204

Delgado, G.; Álvarez, L.; Guzmán, S. Some Biomimetic and Acid Catalyzed Transformations of Melampolides and Heliangolides. Trends in Organic Chemistry. Research Trends (India) 1995, 5, 1-10.

Villarreal, M.L.; Álvarez, L.; Alonso, D.; Navarro, V.; García, P.; Delgado, G. Cytotoxic and Antimicrobial Screening of Selected Terpenoids from Asteraceae species. J. Ethnopharmacology 1994, 42, 25-29. SSDI 0378-8741(94)01098-K

Delgado, G.; Hernández, J.; Chávez, M. I.; Alvarez, L.; Gonzaga, V.; Martínez, E. Di-and Tri-Terpenoid Acids from Lepechinia caulescens. Phytochemistry 1994, 37, 1119-1121. https://doi.org/10.1016/S0031-9422(00)89540-0

Delgado, G.; Hernández, J.; Rios, M. Y.; Aguilar, M. I. Pentacyclic Triterpenes from Cnidoscolus multilobus. Planta Medica 1994, 60, 389-390. DOI: 10.1055/s-2006-959514

Chávez, M. I.; Delgado, G. Isolation and Relay Synthesis of 11α-Hydroperoxy-Diacetyl Hederagenin, A Novel Triterpenoid Derivative from Serjania triquetra (Sapindaceae). Biogenetic Implications. Tetrahedron 1994, 50, 3869-3878. https://doi.org/10.1016/S0040-4020(01)89663-0

Álvarez, L.; Núñez, M.; Pérez, M. C.; Villarreal, M. L.; Delgado, G. Chemical and Biological Study of Astianthus viminalis. Planta Medica 1994, 60, 98. DOI: 10.1055/s-2006-959424

Delgado, G.; Guzmán, S.; Toscano, R. A. Chemical Reactivity of Cis-1(10).Trans-4(5)-Germacradienolides (Melampolides). Additional Derivatives of Schkuhriolide. Anales de la Escuela Nacional de Ciencias Biológicas. (Méx.) 1994, 39, 109-118.

Chávez, M. I.; Delgado, G.; González-Chimeo, E.; Pereda-Miranda, R. Carbon-13 NMR Spectra of Some Pentacyclic Triterpenoids with the Olean-28,13-olide Skeleton. Anales de la Escuela Nacional de Ciencias Biológicas. (Méx.) 1994, 39, 103-108.

Delgado, G.; Cano, A. E.; Ruiz-Cancino, A.; Bye, R.; Linares, E. Polycyclic Diterpenes from the Roots of Iostephane madrensis. Planta Medica 1994, 60, 493. DOI: 10.1055/s-2006-959550

Delgado, G.; Rios, M. Y.; Rodríguez, C. Additional Constituents from Chrysactinia mexicana. Planta Medica 1993, 59, 482. DOI: 10.1055/s-2006-959742

Delgado, G.; García, P. E. 1α-Angeloyloxy-8β,10 DOI: 10.1055/s-2006-959713β-Dihydroxyeremophil-7(11)-en-8α,12-olide from Roldana sessilifolia. Planta Medica 1993, 59, 389. DOI: 10.1055/s-2006-959713

Ruiz Cancino, A.; Cano, A. E.; Delgado, G. Sesquiterpene Lactones and Flavonoids from Artemisia ludoviciana ssp. mexicana. Phytochemistry 1993, 33, 1113-1115. https://doi.org/10.1016/0031-9422(93)85032-M

Aguilar, M. I.; Delgado, G.; Bye, R.; Linares, E. Bisabolenes, Polycyclic Diterpenes and Other Constituents from the Roots of Iostephane heterophylla. Phytochemistry 1993, 33, 1161-1163. https://doi.org/10.1016/0031-9422(93)85041-O

Delgado, G. Organic Natural Products from Some Mexican Plants. Trends in Organic Chemistry. Research Trends (India) 1992, 3, 129-140. 

Delgado, G., Reza-Garduño, R. G., Rios, M. Y., del Rio, F. Phthalides and Monoterpenes of the Hexanic Extract of the Roots of Ligusticum porteri. Planta Medica 1992, 58, 570-571. DOI: 10.1055/s-2006-961555

Delgado, G., and Guzmán, S. Acid Induced Rearrangements of the Melampolide Schkuhriolide. An Alternative Approach to the Oplopane Skeleton. Journal of Chemical Society, Chemical Communications 1992, 606-607. DOI: 10.1039/C39920000606.

Rios, M. Y.; Delgado, G. Terpenoids and Alkaloids from Esenbeckia belizencis. Spontaneous Oxidation of Furoquinoline Alkaloids. Journal of Natural Products 1992, 55, 1307-1309. DOI: 10.1021/np50087a020

Rios, M. Y.; Delgado, G., Polyprenols and Acylphloroglucinols from Esenbeckia nesiotica. Phytochemistry 1992, 31, 3491-3494. https://doi.org/10.1016/0031-9422(92)83713-9

Hernández, J.; Delgado, G. Terpenoids from Aerial Parts of Croton draco. Fitoterapia 1992, 63, 377-378. 

Alvarez, L.; Velasco, A.; Villarreal, M. L.; Delgado, G.; Chávez, M. I.; del Rio, F. Constituents of a Population of Ambrosia hispida and Cytotoxic Evaluation of Its Major Constituent, Hispidulin. Fitoterapia 1992, 63, 366-367. 

Delgado, G.; Sánchez, E.; Hernández, J.; Chávez, M. I.; Alvarez, L.; Martínez, E. New Abietanoid Acid from Lepechinia caulescens. Phytochemistry 1992, 31, 3159-3161. https://doi.org/10.1016/0031-9422(92)83466-C

Bye, R.; Linares, E.; Mata, R.; Albor, C., Castañeda, P.; Delgado, G. Ethnobotanical and Phytochemical Investigation of Randia echinocarpa (Rubiaceae). Anales Inst. Biol. Univ. Nac. Autón. Méx., Ser. Bot. 1991, 62, 87-106. 

Delgado, G.; Rios, M. Y.; Colín, L.; Alvarez, L.; García, P. E. “Chemical Constituents from Borrichia frutescens”. Fitoterapia 1992, 63, 273-274. 

Mata, R.; Calzada, F.; Navarrete, A.; del Rio, F.; Delgado, G. Long Chain Phenols from the Bark of Amphypterygium adstringens. Journal of Ethnopharmacology 1991, 34, 147-154. https://doi.org/10.1016/0378-8741(91)90032-9

Delgado, G.; Rios, M. Y. Monoterpenes from Chrysactinia mexicana. Phytochemistry 1991, 30, 3129-3131. https://doi.org/10.1016/S0031-9422(00)98268-2

Delgado, G.; García, P. E.; Bye, R. A.; Linares, E. Eremophilanolides from Roldana sessilifolia. Phytochemistry 1991, 30, 1716-1719. https://doi.org/10.1016/0031-9422(91)84244-M

Reyes, B.; Delgado, G. Furanoeremophilanolides from Senecio andreuxii. Heterocycles 1990, 31, 1405-1408. DOI: 10.3987/COM-90-5394

Pereda-Miranda, R.; García, M.; Delgado, G. Structure and Stereochemistry of New-δ-Pyrones from Hyptis oblongifolia. Phytochemistry 1990, 29, 2971-2974. https://doi.org/10.1016/0031-9422(90)87117-D

Pereda-Miranda, R.; Delgado, G.; Triterpenoids and Flavonoids from Hyptis albida. Journal of Natural Products 1990, 53, 182-185. DOI: 10.1021/np50067a028

Delgado, G.; Rios, M. Y. Triterpenoids from Salvia longystyla. Planta Medica 1990, 56, 243. DOI: 10.1055/s-2006-960943

Navarrete, A.; Mata, R.; Delgado, G. Alkyl Anacardic Acids from Amphypterygium adstringens. Planta Medica 1989, 55, 579. DOI: 10.1055/s-2006-962108

Delgado, G.; Hernández, J.; Pereda-Miranda, R. Triterpenoid Acids from Cunila lythrifolia. Phytochemistry 1989, 28, 1483-1485. https://doi.org/10.1016/S0031-9422(00)97769-0

Reynolds, W. F.; Delgado, G.; Chávez, M. I.; Díaz, E. 2D-NMR Studies and the Unambiguous Assignation of 1H and 13C Chemical Shifts of Cryptomeridiol. Spectroscopy International Journal 1988, 6, 113-122. 

Álvarez, L.; Delgado, G. Acid Catalyzed Transformations of the Heliangolide 15−Hydroxy-Acetylleptocarpin. Journal of Organic Chemistry 1988, 53, 5527-5530. DOI: 10.1021/jo00258a023

Delgado, G.; Reza-Garduño, R. G.; Toscano, R. A.; Bye, R. A.; Linares, E. Secondary Metabolites from the Roots of Ligusticum porteri. X-Ray Structure of Z-6.6',7.3'a-Diligustilide. Heterocycles 1988, 27, 1305-1312. DOI: 10.3987/COM-87-4476

Mata, R., Castañeda, P., Camacho, M. R., and Delgado, G. Chemical Studies on Mexican Plants Used in Traditional Medicine V. Cucurbitacin Glycosides from Cigarrilla Mexicana. Journal of Natural Products 1988, 51, 836-839. DOI: 10.1021/np50059a003

Delgado, G.; Chávez, M. I.; and Álvarez, L. New Seco-Pseudoguaianolides and Other Terpenoids from a Population of Ambrosia confertiflora. Journal of Natural Products 1988, 51, 83-87. DOI: 10.1021/np50055a011

Reguero, M. T., Mata, R., Bye, R., Linares, E., and Delgado, G.; Chemical Studies on Mexican Plants Used in Traditional Medicine II. Cucurbitacins from Hintonia latiflora. Journal of Natural Products 1987, 50, 315-316. DOI: 10.1021/np50050a050

Delgado, G.; Garduño, J. Pyranocoumarins from Arracacia nelsonii. Phytochemistry 1987, 26, 1139-1141. https://doi.org/10.1016/S0031-9422(00)82365-1

Romo de Vivar, A.; Delgado, G.; Soriano García, M.; Toscano, R. A.; Huerta, E.; Reza-Garduño, R. G. “Sesquiterpene Lactones from a Population of Helenium integrifolium”. Journal of Natural Products 1987, 50, 284-286. DOI: 10.1021/np50050a037

Delgado, G.; Alvarez, L.; Soriano-García, M.; Toscano, R. A.; Mata, R.; Pereda-Miranda, R. “Stereochemistry of the Ester Side Chain of the Germacranolides of Viguiera hypargyrea”. Journal of Natural Products 1987, 50, 273-276. DOI: 10.1021/np50050a034

Delgado, G.; Alvarez, L.; Mata, R.; Pereda-Miranda, R.; Romo de Vivar, A. Terpenoids from Viguiera latibracteta and Viguiera greggii. Journal of Natural Products 1986, 49, 1165. DOI: 10.1021/np50036a028

Pereda-Miranda, R.; Delgado, G. Flavonoids from Salvia nicholsoniana. Journal of Natural Products 1986, 49, 1160. DOI: 10.1021/np50048a050

Delgado, G.; Alvarez, L.; Huerta, E.; Romo de Vivar, A.; Mata, R. Carbon-13 NMR Spectra of Some Pseudoguaianolides. Magnetic Resonance in Chemistry 1987, 25, 201-202. https://doi.org/10.1002/mrc.1260250304

Delgado, G.; Guzmán, S.; Romo de Vivar, A. Schkuhridin A and Schkuhridin B, New C14β,H5α-Elemanolides from Schkuhria schkuhrioides. Phytochemistry 26, 755-759 (1987). https://doi.org/10.1016/S0031-9422(00)84780-9

Mata, R.; Navarrete, A.; Alvarez, L.; Pereda-Miranda, R.; Delgado, G.; Romo de Vivar, A.; Flavonoids and Terpenoids of Chenopodium graveolens. Phytochemistry 1987, 26, 191-193. https://doi.org/10.1016/S0031-9422(00)81509-5

Delgado, G.; Cárdenas, X.; Álvarez, L.; Romo de Vivar, A.; Pereda-Miranda, R. New Oleanane and Pimarane Diterpenoids from Lepechinia glomerata. Journal of Chemical Research (S) 1986, 286-287; (M) 1986, 2565-2579. 

Pereda-Miranda, R.; Delgado, G.; Romo de Vivar, A. An Abietane Diterpenoid from Salvia sapinae. Phytochemistry 1986, 25, 1931-1933. https://doi.org/10.1016/S0031-9422(00)81177-2

Pereda-Miranda, R.; Delgado, G.; Romo de Vivar, A. New Triterpenoids from Salvia nicholsoniana. Journal of Natural Products 1986, 49, 225-230. DOI: 10.1021/np50044a005

Romo de Vivar, A.; Delgado, G. Los Metabolitos Secundarios de Viguiera Compositae, Heliantheae). Química e Implicaciones Quimiotaxonómicas. Bol. Soc. Chil. Quím. 1985, 30, 79-100. 

Alvarez, L.; Mata, R.; Delgado, G.; Romo de Vivar, A. Sesquiterpene Lactones from Viguiera hypargyrea. Phytochemistry 1985, 24, 2973-2976. https://doi.org/10.1016/0031-9422(85)80038-8

Delgado, G.; Pereda-Miranda, R.; Romo de Vivar, A. “4-Deacetoxy-10-Epi-Olguine, a New δ-Lactone from Hyptis oblongifolia (Bentham) Labiatae”. Heterocycles 1985, 1869-1872. DOI: 10.3987/R-1985-08-1869

Delgado, G.; Alvarez, L.; Romo de Vivar, A. 15-Hydroxy-Acetyl-Erioflorin and Other Constituents from Viguiera linearis. Phytochemistry 1985, 24, 2736-2738. https://doi.org/10.1016/S0031-9422(00)80712-8

Romo de Vivar, A.; Delgado, G.; Huerta, E. Structure and Stereochemistry of Mexicanin G, An Intermediate in the Biogenesis of Helenanolides. Phytochemistry 1985, 24, 2977-2979. https://doi.org/10.1016/0031-9422(85)80039-X

Romo de Vivar, A.; Delgado, G. Structure and Sterochemistry of Mexicanin F, A Novel Dimeric Nor-Sesquiterpene Lactone from Helenium mexicanum. Tetrahedron Letters 1985, 579-582. https://doi.org/10.1016/S0040-4039(00)89152-2

Mata, R.; Delgado, G.; Romo de Vivar, A. Sesquiterpene Lactones from Artemisia klotchiana. Phytochemistry 1985, 24, 1515-1519. https://doi.org/10.1016/S0031-9422(00)81057-2

Delgado, G.; Cárdenas, H.; Peláez, G.; Romo de Vivar, A.; Pereda-Miranda, R. Terpenoids from Viguiera excelsa and Viguiera oaxacana. Journal of Natural Products 1984, 47, 1042-1045. DOI: 10.1021/np50036a028

Delgado, G., Álvarez, L., and Romo de Vivar, A. 15-Oxo-Zoapatlin, A Diterpene Lactone from Viguiera maculata. Phytochemistry 1984, 23, 2674-2675. https://doi.org/10.1016/S0031-9422(00)84125-4

Delgado, G. and Romo de Vivar, A. Ent-Kaurenoid Methyl Esters from Viguiera stenoloba Structural Revision of Stenolobin and Its Biomimetic Conversion to Zoapatlin. Chemistry Letters (Japan) 1984, 1237-1240. https://doi.org/10.1246/cl.1984.1237

Delgado, G.; Hernández, H.; Romo de Vivar, A. Structure and Stereochemistry of Elemansckuhriolide. Melampolides as Possible Biogenetic Precursors of C14α,H5β-Elemanolides. Journal of Organic Chemistry 1984, 49, 2994-2996. DOI: 10.1021/jo00190a027

Delgado, G.; Romo de Vivar, A.; Cárdenas, J.; Pereda-Miranda, R.; Huerta, E. Ent-Beyerene and Ent-Atisene Diterpenoids from Viguiera insignis. Phytochemistry 1984, 23, 2285-2288. https://doi.org/10.1016/S0031-9422(00)80536-1

Mata, R.; Delgado, G.; Romo de Vivar, A. Sesquiterpene Lactones from Artemisia mexicana var. angustifolia. Phytochemistry 1984, 23, 1665-1668. https://doi.org/10.1016/S0031-9422(00)83464-0

Delgado, G.; Álvarez, L.; Romo de Vivar, A. Terpenoids and a Flavan-3-ol from Viguiera quinqueradiata. Phytochemistry 1984, 23, 675-678. https://doi.org/10.1016/S0031-9422(00)80405-7

Delgado, G.; Romo de Vivar, A.; Ortega, A.; Cárdenas, J.; Schlemper, E. O. Diterpenoids from Viguiera insignis. Phytochemistry 1983, 22, 1227-1230. https://doi.org/10.1016/0031-9422(83)80227-1

Romo de Vivar, A.; Reyes, B.; Delgado, G., Schlemper, E. O. Constituents of Pluchea sericea. Structure and Stereochemistry of (11S)-11,13-Dihydrotessaric Acid. Chemistry Letters (Japan) 1982, 957-960. https://doi.org/10.1246/cl.1982.957

Romo de Vivar, A.; Pérez, A. L.; León, C.; Delgado, G. 11,13-Dehydroeriolin, Schkuhrioidin and Schkuhriolide, Germacranolides from Schkuhria species. Phytochemistry 1982, 21, 2905 -2908. doi: 10.1016/0031-9422(80)85065-5

Delgado, G.; Romo de Vivar, A.; Herz, W. Sesquiterpene Lactones from Viguiera species. Phytochemistry 1982, 21, 1305-1308. Doi: 10.1016/0031-9422(82)80130-1

Romo de Vivar, A., Delgado, G., Guerrero, C., Reséndiz, J. y Ortega, A. Estudio de Viguieras. Estructura de la Viguiepinina y Corrección de la Viguiestenina. Revista Latinoamericana de Química 1978, 9, 171-174.